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Non-iLab, JHU ICTR Core Facilities

Overview of Services

We offer a variety of resources (not currently live in iLab) to members of the Johns Hopkins research community who are currently preparing or executing clinical research. From clinical infrastructure, nursing and laboratory services, we are prepared to address the most pressing needs of clinical investigators. We strive to support human subject research at all phases of translation Support human subject research at all phases of translation.
The ICTR laboratories provide coordinated help across several related programs, all focused on the foundational components required to effectively translate new drugs, biologics, vaccines, devices, biomarkers and diagnostics into clinical trials and eventually clinical practice.
The ICTR provides discounted rates when usage is access via CONNECTION REQUEST only or for requests submitted through ICTR resources found in iLab.
(Note:  When the lab is selected, I would like the end user to be taken directly to Connection Request as that is the only way they can receive a discount and the ICTR gets to document the credit.  We need to document the credit for reporting on our grant.)
Click here to submit an ICTR Connection Request (from our website)






Name Role Phone Email Location
Barbara Daily



Name Description
Biologics Translational Program 



This lab offers: Biologic product development and testing Consultative support for biologic development Preclinical testing to clinical production for early phase clinical testing Good Manufacturing Practices (GMP) facility and expertise to produce and maintain (stability testing Cell lines Gene vectors Antibodies Peptides.


Click here to submit an ICTR Connection Request


Biostatistics Program 


All CRU protocols are reviewed by a member of the Biostatistics Core prior to approval, and consultations with a Core biostatistician are strongly encouraged for all investigators who do not already have biostatistical support as part of their funded protocols.

In conjunction with the Biostatistics Center, ICTR offers researchers access to a research-related consulting service. The goal of the service is to promote the appropriate use of biostatistics in the design, implementation, and interpretation of clinical and translational research studies.

The Biostatistics Center supports JHU faculty with primary appointments by providing a maximum of 5 hours of free support per clinical and translational research project through the ICTR. Consultants can assist with: research study design, design of data collection systems and instruments, data entry and validation, data management and quality assurance, statistical analysis and data interpretation, and professional and scientific report-writing.

Once projects obtain independent funding, services will be provided on a fee-for-service basis. The goal of these consultations is to advise and educate the researcher by enabling him or her to both design and execute well-constructed studies and analyze the study data collected.

TIME FRAME: Please contact the Biostatistics Center as early as possible before your deadlines and with an awareness of the following guidelines:

  • Abstracts: The Center generally needs at least one month. Ideally, we hope you will give us two months or more. If it is less than one month before the deadline, we may be able to assist with some simple summary statistics; however we cannot guarantee more complicated analyses, such as multiple variable analyses.
  • Grants: The Center typically needs at least three weeks for new grant submissions. If it is a re-submission, we need at least two weeks to improve your score.
  • Manuscript Review: The Center requires a minimum of two weeks for manuscript reviews.

As the deadline approaches, the likelihood that we can provide helpful statistical support diminishes. On a case by case basis, The Biostatistics Center may decline requests that are too close to the deadline to provide anything useful.

Within 3-5 working days of receipt of a request, a consultant will be assigned and in contact with you to arrange an initial meeting.  To request a consultation with the Biostatistics Center through Connection Request, click here.

WALK IN SESSIONS: The Biostatistics Core also offers brief consultation through its walk-in consultation service. The walk-in session is designed to provide a quick evaluation of statistical issues concerning a clinical / translational research project to provide an answer during the consultation or to set up a subsequent appointment to work on the issues further.

East Baltimore Campus Walk-In Clinic

Bayview Campus Walk-In Clinic

Hours: 1pm – 2pm on Tuesdays and 12pm – 1pm on Fridays
Location: 301 Building on Bayview Campus, Room 2202

The clinics are “first come, first serve.”

The Bayview Clinic is manned by Drs. Nae-Yuh Wang ( and Dhananjay Vaidya (, and may be cancelled when they are out of office. Please email them to confirm clinic hours before coming by.


Click here to submit an ICTR Connection Request

Cardiovascular Imaging Laboratory 


The Cardiovascular Imaging Laboratory is located at the Bayview CRU and is supervised by Pamela Ouyang, MBBS, ICTR Deputy Director and Director of the Johns Hopkins Women’�s Cardiovascular Health Center. The Core provides echocardiographic and carotid imaging for approved CRU protocols, as well as measurement of endothelial function and arterial stiffness.

The Cardiovascular Imaging Laboratory provides the following services and equipment:


Echocardiograms are performed on a Toshiba Artida ultrasound system. All cardiac studies are stored digitally and analyzed using the Philips Excelera System. Image acquisition and analysis protocols can be customized to meet the unique needs of the investigator.

Carotid IMT
Carotid imaging is performed on a Toshiba Aplio ultrasound system. Using commercially available state of the art equipment that includes automated border detection, the core lab can accurately measure carotid intima-medial thickness and distensibility.

Brachial Reactivity Studies
Brachial ultrasound studies are performed on a Toshiba Aplio system. A high frequency (15Mhz) ultrasound transducer is held in place by a mounted stationary device to insure reproducibility of brachial reactivity measures. Endothelial function tests are performed using both cuff inflation and nitroglycerin to induce brachial flow mediated dilatation (FMD). Analysis of both brachial diameter and flow velocity is performed using state of the art commercially available equipment with automated edge detection.

Endothelial Function
The EndoPat or Endothelix systems both measure endothelial response to reactive hyperemia following the release of arm bloodflow occlusion. The EndoPat system measures changes in bloodflow volume in response to reactive hyperemia, whereas the Endothelix measures changes in fingertip temperature

Vascular Stiffness
Vascular Stiffness is measured as the the pulse wave augmentation index (AGI). It is derived from measurement of the pulse wave contour and is a measure of the pressure wave is reflected back during pulse wave cycle, which is a measure of vascular stiffness. AGI can be obtained from the EndoPat and SphygMoCor, each of which measure the radial artery pulse wave.

Click here to submit an ICTR Connection Request

Computational Medicine Program 


The Computational Medicine Core was created to support innovative biomedical research programs at Johns Hopkins University. It offers services and consulting for investigators interested in mathematical modeling of complex biological systems in health and disease. Models may be used to achieve quantitative understanding of and to generate hypotheses about disease mechanisms and treatments that can then be tested in the laboratory and/or clinic.

Our goal is to serve as a scientific resource for investigators where bioengineers, computer scientists, and physicists will help physicians and basic scientists develop computational models. We can provide consulting on: selecting the class of models that are most appropriate given the data and scientific questions at hand; guidance on how to formulate and test models;  advice on implementation of computational models using different programming languages and environments, hardware considerations, and data visualization methods.

We will work as a consultancy group, offering specific experience in modeling of a variety of biological systems. The personnel consist of the faculty and staff of ICM, with initial consulting provided by Dr. Pawel Kudela. Our model capabilities currently include:

  • Computational molecular medicine – Feilim Mac Gabhann, Rachel Karchin, Joel Bader, Donald Geman
  • Computational Neuroscience – William S Anderson, Pawel Kudela, Srideva Sarma
  • Computational cell biology and physiological medicine – Raimond L. Winslow
  • Cardiac electromechanics modeling – Natalia Trayanova, Fijoy Vadakkumpadan
  • Biological fluid dynamics modeling – Rajat Mittal, Jung-Hee Seo
  • Computational anatomy – Michael Miller, Laurent Younes, Tilak Ratnananther
  • Agent based models – Joshua Epstein
  • Data modeling and machine learning – Suchi Saria, Mauro Maggioni

We accept consultations from investigators throughout the Schools of Medicine and Public Health. Investigators are asked to submit a 1-2 page description of their research to A series of consultation meetings will then be arranged to outline the programming and research needs and to schedule the project.

WALK IN SESSIONS: The Computational Medicine Core offers walk-in consultation service to answer quick questions about the use of computers to simulate and study the behavior of biological systems at multiple levels. The walk-in session is designed to provide a quick evaluation of a clinical / translational research project needs or to set up a subsequent appointment to work on the project further. Walk-in consultations are offered each Friday between 10 am – 4 pm in Hackerman 316D (Homewood Campus).

For more information, visit:  and

Click here to submit an ICTR Connection Request

Drug Analysis Unit 


The Drug Analysis Unit provides support for drug development activities to faculty and to solicit use by faculty of Core expertise and facilities. Activities include consultative expertise and laboratory support. The unit offers support in the areas of: Small molecule assay development Sample analysis for pre-clinical and clinical studies Pharmacokinetic data analysis support Consultative support for pre-clinical study design  


Click here to submit an ICTR Connection Request

Drug Development Unit 

Click here to submit an ICTR Connection Request (from our website)



The Drug Development Unit provides: Consultative support for early phase clinical drug development Protocol design and data analysis support Early phase clinical study support   

Drug Screening Library Unit 


The Drug Screening Library Unit maintains, distributes, and screens drug library (FDA approved) compounds.  This unit is ideal for re-purposing licensed drugs by screening activity against new targets. For more information, contact Jun Liu, PhD.  


Click here to submit an ICTR Connection Request

Genetic Translational and Technology Program 


The Genetics Translational Technology Program bridges the gap between clinical genetic testing and research-driven molecular technologies with consulting and laboratory services and assistance with translation of molecular technologies to the clinical environment. The program provides: A consultation for the development and conduct of genetic based sequencing and diagnostic assays for clinical testing Clinical assay development services Exome and whole genome sequencing using next generation sequencing (NGS) technologies Partnership with the Kennedy Krieger Institute’s Cytogenetics Laboratory for SNP Array Analysis.


Click here to submit an ICTR Connection Request  


ICTR Non-iLab: Cores, Laboratories & Programs

Search available services: View: by category alphabetically
Biologics Translational Program (1)
Biostatistics (1)
Cardiovascular Imaging Laboratory (1)
Computational Medicine Program (1)
Drug Analysis Unit (1)
Drug Development Unit (1)
Drug Screening Library Unit (1)
Genetic Translational and Technology Program (1)


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